Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

v
n. 远景,看法,透视
在3月2号,北韩政府网站我们民族之间警告北韩将对任何气球投放展开"炮弹和导弹的攻击,而不只是几下枪击"。
我立刻赞同了克雷格和尼尔关于艾伦是今年颁奖礼最合适的主持的想法。我们希望举办一场娱乐、吸引人而又有趣的颁奖礼。
如下是我们对中国2014年的10个预测
2017年我国继续同步提高企业和机关事业单位退休人员的基本养老金水平,惠及1亿多人。
Accelerating price growth for new housing in cities across China lost more steam in November amid a flurry of purchasing curbs in major cities, though price gains from a year earlier remained comfortably in double-digit territory.
The report shows that compared with that in 2015, the percentage of graduates to start up business are significantly decreased from 6.3% to 3.1% in 2016.
Ladies and gentlemen, may I welcome you to the Bad Manners Awards 2016?
对家长而言,整天抱着孩子非常费劲,尤其是孩子越来越大、越来越重的时候。
I want to be in your arms this New Year.我要在你的怀抱里度过今年的春节。
乔布斯在苹果大会上作专题演讲后展示MacBook Air ,2008年,1月15日,旧金山
扎实有效去产能。
AFI TV Programs of the Year
Interbrand的全球首席执行官杰斯·弗兰普顿表示:“苹果、谷歌和可口可乐是世界上最有价值的品牌。因为他们的财务实力雄厚,品牌具有强大的号召力,这是其竞争对手无法比拟的。”
该报告显示,社交媒体,尤其是微信,过去一年里在40岁以上人群中变得越来越受欢迎。
一家国际医学杂志撤销了107篇中国学术论文,由此引发了人们对中国学术诚信的关注。被撤稿的作者多数是临床医生。
She argues, however, that the problems with lower liquidity of ETFs in Asia are a symptom of a fund distribution system that fails to incentivise ETF sales by intermediaries. “I don't think there is a quick fix, but you would see a pick-up if Asia moves to a fee-based model,” she says.
6. Gene therapy comes good.
它会自然生长成模子的形状。
另外一件性玩具则显然属于中国皇室。
15. 有趣的巧合。环球影业是题材最具多样性的制片公司之一,它发行了《生活残骸》,也发行了《冲出康普顿》,还有《泰迪熊2》(Ted 2)。环球影业的女导演也是最多的,12月初,它占据了今年24%的市场份额。
12岁的年纪,大多数的小女孩都还在向父母争取打耳洞的机会,努力适应高中生活,从青少年时代开始为将来做准备。
夏普利对这一主题提出了早期的理论,在20世纪50年代和60年代利用博弈论来分析不同的匹配方式。与美国经济学家大卫?盖尔一起,他开发了一个数学公式10个男人和10个女人如何配对才能保证没有人会受益于配对伙伴。虽然这可能有一点影响到结婚和离婚,他们开发的算法已经被用于更好地理解许多不同的市场。
Annual prices had been rising as much as 9.6 per cent at the start of this year but they've cooled since then as the economy slows and many mid-sized Chinese cities suffer from a glut of apartments.


这位官员表示,相比其他职位来说,那些对教育背景或工作经历没有特殊要求的职位更受欢迎,近些年报名人数达到数千人的基本上都是这种职位。
为大批来自欧洲经济区以外的学生安排签证难度较大,这在一定程度上解释了为何英国商学院在国际课程经验方面表现奇差,有14所英国商学院位于这项指标排名的后半部分。
Best Companies rank: 1


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

We'll start our review with the South American nations, and who else could we begin with, but the hosts Brazil. Rewind 18 months and they looked like they'd be struggling, but the appointment of 'Big Phil' Scolari has been inspired, and he's brought a belief to the team that was previously missing. Last years 3:0 demolition of Spain in the Confederations Cup final shocked many experts, and all of a sudden the Brazilians have expectations on them. Whilst you can't argue with that scoreline, we still wonder if Brazil have the firepower to win such a long tournament. Neymar is expected to conjure up the magic, but they're relying on Fred to come up with the goals. No disrepect to Fred, but the last two Brazilian teams to win the World Cup, in 2002 and 1994, could count on the likes of Ronaldo and Romario to lead the front line, two genuine legends of the game.
联系方式:Debbie McNally, Lakes Sotheby’s International Realty, (612) 388-1790; debbiemcnally.com
Sam Smith is a fluid soul man, with style channeling Otis Redding, Aretha Franklin and Ray Charles alongside modern icons like Amy Winehouse and Adele.
谷歌公司一名发言人在上周三时表示,该公司意识到“这是一个错误,哈维尔是无心之失”。

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

葡萄牙的成就说明这种转变是可行的,它为各国政府和能源公司提供了一个实实在在的范例,也告诉他们为什么现在应该投资太阳能、风能、波浪能和其他可再生技术。

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

在导演阿方索?卡隆(Alfonso Cuaron)和同事们(其中包括知名电影摄影师艾曼努尔?卢贝兹基(Emmanuel Lubezki)、制片设计师安迪?尼克尔森(Andy Nicholson)和编剧霍纳斯?卡隆(Jonas Cuaron))的共同努力下,《地心引力》丰富了电影的拍摄手法。《美国电影摄影师》(American Cinematographer)杂志上个月的封面故事刊载了关于《地心引力》制作过程的文章,对电影技术感兴趣的读者可以一探究竟。读者们可以在网上阅读该杂志。不过任何看过《地心引力》的观众都已经领会到了该片的情感内涵,这部电影把观众们带进入了一个寂静危险的外太空和一个深度愉悦的内心世界。
继《菲洛梅娜》后,朱迪.丹克和斯蒂芬.弗雷斯这对出色的组合四年后再度联手。该片由李荷担任编剧,讲述了维多利亚女王与年轻印度男仆之间的友情。艾迪.伊扎德看来是官方授意的威尔士亲王人选;演员阵容还包括奥莉维亚.威廉姆斯,蒂姆.皮戈特.史密斯以及同样出演了《总督之房》的西蒙.卡洛和迈克尔.甘本。

Guangzhou, Shenzhen, Hangzhou, Wuhan and Nanjing have been ranked as the top five cities for opportunity in China, according to a report jointly launched by PricewaterhouseCoopers and the China Development Research Foundation.
Not only does its small cohort of about 50 allow the school to select highly experienced participants, it also creates a strong bond between them.
Over 11 million new urban jobs, and a registered urban unemployment rate within 4.5 percent.
这是007系列电影最佳主题曲之一,但实际上并没有在片头演奏,所以我们把它放在荣誉推荐的第一位。这首浪漫的曲子呼应了电影情节的发展,最终詹姆斯·邦德遇到了真爱。(可惜他们的恋情维持不久便结束了。)路易斯·阿姆斯特朗运用了他标志性的颤音,听者心弦颤动,一个经典诞生了。
Chester Bennington
Successful CEOs tend to follow a structured, daily schedule of rising early, exercising, having snacks on hand for fuel and socializing many evenings of the week.

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


八月全国建材家居景气指数攀升


References

1. Cision PR Newswire. Fifth annual Pulse of Online Health survey finds 66% of Americans eager to leverage digital tools to manage personal health. Posted 24 February 2015. Accessed 28 August 2017. www.prnewswire.com/news-releases/fifth-annual-pulse-of-online-health-survey-finds-66-of-americans-eager-to-leverage-digital-tools-to-manage-personal-health-300039986.html.

2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. www.azumio.com/s/instantheartrate/index.html. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. www.azumio.com/s/sleeptime/index.html. 

33. RelaxLine. BellyBio. Accessed 28 August 2017. https://itunes.apple.com/ca/app/bellybio-interactive-breathing/id353763955?mt=8.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.


纽约人向专栏提出的问题,不仅取决于他们的个人情况,还取决于当今的重大问题,比如住房成本上升、士绅化、豆腐渣工程。最终,2014年成为了一个一切都在增长的年份,增长的包括房价、租金,以及最重要的——楼盘数量。根据纽约房地产委员会(Real Estate Board of New York)的数据,10月批准建设的单元达到了16700套。
The Big Bang Theory is not short on geniuses. Not only is the show about highly intelligent scientists, but cast member Mayim Bialik has a Ph.D. in Neuroscience. So it should come as no surprise that the cast would want to show off their intelligence and attention to detail. In Sheldon and Leonard's apartment, there's a large white board. The two roommates use the board frequently for everything from actual work that Leonard or Sheldon has brought home, or to decide whether to eat before or after the new Spider-Man movie.
1.戛纳也有软肋
sur下面+rog要求…要求做下去…代理+ate表名词,“人或地位”→代理人,代替品
《海底总动员2》将于2016年6月17日上映。
二十多年的旨在减少温室气体排放增长的全球谈判几乎没有进展。但在2014年,人们看到了针对这个问题的大规模政治行动的迹象,在30多万人去年九月在纽约举行大游行之后,世界各地的其他城市中也有数以万计的人走上街头。
['li:kid?]
三大能源机构近期表示,今年石油输出国组织(Organization of the Petroleum Exporting Countries, 简称:欧佩克)以外国家的原油产量将增加,其中大部分来自美国的页岩油。除此之外,由于伊朗、伊拉克和利比亚可能会增产,中东地区的原油产量也许会增加数百万桶。所有这些势必会令油价承压。
联合国世界知识产权组织(WIPO)、英士国际商学院和美国康奈尔大学联合发布的年度报告显示,全球第二大经济体正在赶追创新领域那些传统的领先者。目前,第一集团主要是由瑞士、瑞典、英国和美国引领。
Forget giving at least two weeks notice, finessing an exit interview, and tactfully networking your way out the door. Some people are in too big a hurry for any of that.

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



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Halpern SD, Ubel PA, Caplan AL, Marion DW, Palmer AM, Schiding JK, et al. Solid-organ transplantation in HIV-infected patients. N Engl J Med. 2002;347:284-7.

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In the next few years, by 2018, theincrease to $1.3 trillion will be due to about $100 billion on hepatitis Cdrugs, the same sums spent on cancer treatment, and $78 billion on diabetescare.
共和党候选人时常表现出不确定以及偶尔会忘了自己要说的,好像在试图记住他的简要笔记。当奥巴马从一开始就咄咄逼人时他开始出汗,在伊朗、伊拉克、俄罗斯以及美国的军费开支的交流中他才表现得更好。
The year before, Taiwanese anti-China protesters chose the sunflower as the symbol for their cause.
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Liu Fei was also a half-brother of the Emperor Wu of Han who ruled from 141BC to 97BC.

  • Only the first three authors are listed, followed by "et al."
  • 如何选购外墙保温材料?
  • 东方家园大连店重启高端家居商场再自救


The United Kingdom ranks No. 3 overall. It ranks No. 4 in Power and No. 5 in Cultural Influence.
读:口齿-教练要求口齿伶俐。

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